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Stacie Gutowski - Advisor, Andres Garcia, PhD
"Polymeric Coatings to Reduce Inflammation to Neural Electrodes"
Neuroprosthetic devices have the potential to restore functionality to patients with injuries and diseases that affect brain function and signaling to the body. We are engineering polymeric coatings for neural electrodes to reduce inflammation in the surrounding tissue environment. Testing includes both in vitro and in vivo components to observe the effect of these coatings on the tissue response to chronically implanted electrodes.
Song Seto - Advisor, Johnna Temenoff, PhD
"Cathepsin Activity During Tendon Overuse in a Rat Model"
In order to design appropriate treatments for rotator cuff tendinopathy, cell-mediated events that occur during tissue degeneration need to be studied. Using a rat running model of tendon overuse, we studied cathepsin activity using multiplex zymography during 8 weeks of overuse activity. Higher cathepsin activity in overused tendons indicates that these proteases play an important role in tendon degeneration.