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"Perineuronal Nets: A Decade Later"
Advisor, Ravi Bellamkonda, PhD
For the past decade, perineuronal nets (PNNs) have been considered a critical regulator of both neuroplasticity and neural regeneration. We look at the specific function of PNNs in the rodent barrel cortex and how this and other studies have begun to question this model.
"A Single Cell Approach to Analysis of Heterogeneity Within Immune Cell Populations"
Advisor, Melissa Kemp, PhD
A growing body of evidence shows that even genetically identical cells can be phenotypically heterogeneous, and that this can have functional consequences. We theorize that such non-genetic differences affect immune function and use emerging techniques for single cell analyses to detect such heterogeneity in immune cell populations. The resulting information will help us develop methods for data-driven predictions of individual immune profiles.