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News - Bioengineering and Bioscience

Cichlid brain development4

Pathway Competition Affects Early Differentiation of Higher Brain Structures

April 26, 2013 — A new study in fish shows how the strength and timing of competing molecular signals during brain development has generated natural and presumably adaptive differences in a brain region known as the telencephalon -- much earlier than scientists had previously believed.

Prof. Howard Weiss

New Study Offers Insight on Pandemic Flu

April 25, 2013 — A recent study published in PLoS ONE, a peer-reviewed scientific journal, provides new information for public health officials on mitigating the spread of infection from emerging flu viruses

Steve Potter

Creative Assignments Lead to Teaching Success

April 15, 2013 — Steve Potter never wanted to be a conventional professor.

Anemo Check

Anemia Testing Technology Wins Ideas to SERVE Competition

April 11, 2013 — Anemo Check's technology to improve the accuracy and affordability of testing for anemia around the world won first place in the 2013 Ideas to SERVE (I2S) Competition at Georgia Tech Scheller College of Business.

Stem cell separation microfluidics1

Adhesive Differences Enable Separation of Stem Cells to Advance Potential Therapies

April 7, 2013 — A new separation process that depends on an easily-distinguished physical difference in adhesive forces among cells could help expand production of stem cells generated through cell reprogramming. By facilitating new research, the separation process could also lead to improvements in the reprogramming technique itself and help scientists model certain disease processes.

Obama BRAIN Announcement

Georgia Tech Researchers Attend White House Event Announcing New BRAIN Initiative

April 2, 2013 — President Barack Obama today announced a major new commitment to fund research to map the activity of the human brain. The goal of this grand challenge project is to develop new technologies that reveal in real time how brain cells and neural circuits interact to process information. The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative will be launched with $100 million in the President's FY 2014 Budget.

Staining Tumors Blue

New Nanotechnology Research Study Turns Brain Tumors Blue

March 27, 2013 — Georgia Techn and Children's Healthcare of Atlanta announce new technique that increases precision in brain tumor removal.

Sherry Farrugia

Farrugia to Manage Georgia Tech/Children's Healthcare of Atlanta Research Partnership

March 27, 2013 — The Georgia Institute of Technology and Children’s Healthcare of Atlanta are advancing their commitment to collaborative research through enhanced management of their vast joint research portfolio.

Bob Guldberg

IRI Intros: 5 Questions with Bob Guldberg

March 27, 2013 — This article is the second in a series of Q&As to introduce the Tech community to the eight IRIs and their directors. In this installment, Executive Director Bob Guldberg answers five questions about the Parker H. Petit Institute for Bioengineering & Bioscience.

AFM Cantilever for Actin Study

Mechanical Forces Control Assembly and Disassembly of a Key Cell Protein

March 20, 2013 — Researchers have for the first time demonstrated that mechanical forces can control the depolymerization of actin, a critical protein that provides the major force-bearing structure in the cytoskeletons of cells. The research suggests that forces applied both externally and internally may play a much larger role than previously believed in regulating a range of processes inside cells.

Microneedle for Eye Treatment

Startup Launched from Georgia Tech-Emory University Research Receives $7.9 Million

March 18, 2013 — Clearside Biomedical, Inc. an Atlanta-based ophthalmic pharmaceutical company launched from research at Emory University and the Georgia Institute of Technology, has received $7.9 million in funding to continue drug and technology development for treatment of ocular diseases.

Pamela Bhatti  with cochlear implant

Improved Hearing Anticipated for Implant Recipients

March 18, 2013 — A team of researchers at the Georgia Institute of Technology has developed a new type of interface between cochlear implant devices and the brain that could dramatically improve the sound quality of the next generation of implants. Cochlear implants help deaf individuals perceive sound.

GoNow

GoNow Bladder Technology Wins Business Plan Competition

March 12, 2013 — Technology that could help spinal-cord injury sufferers control their bladder by remote control won first place ($10,000) in the 2013 Georgia Tech Business Plan Competition.

Neural Synchrony

Neural “Synchrony” May be Key to Understanding How the Human Brain Perceives

March 11, 2013 — In a perspective article published in the journal Nature Neuroscience, biomedical engineering professor Garrett Stanley detailed research progress toward “reading and writing the neural code.” The neural code details how the brain’s roughly 100 billion neurons turn raw sensory inputs into information we can use to see, hear and feel things in our environment.

Ravi Bellamkonda

Medical and Biological Engineering Group Names Bellamkonda President-Elect

March 10, 2013 — The American Institute for Medical and Biological Engineering (AIMBE) has named Ravi Bellamkonda as the organization’s president-elect. He will begin his term as president in 2014.

Industry Agreements Streamline Contracting Process

March 1, 2013 — The Office of Industry Engagement — part of the Georgia Tech Research Corporation (GTRC) — has developed four contract mechanisms that enable industry to engage with Georgia Tech researchers at all stages of R&D.

Nicholas Hud in lab

Molecules Assemble in Water, Hint at Origins of Life

February 20, 2013 — Researchers have spontaneously assemble "proto-RNA bases" in water,  suggesting that the genes of life could have gotten started from these or similar molecules.

Evolving Molecules2

Designer Blood Clots: Artificial Platelets Could Treat Injured Soldiers on the Battlefield

February 15, 2013 — When it comes to healing the terrible wounds of war, success may hinge on the first blood clot – the one that begins forming on the battlefield right after an injury.

Cyclic Mechanical Reinforcement

Sticky Cells: Cyclic Mechanical Reinforcement Extends Longevity of Bonds Between Cells

February 14, 2013 — A new study provides insights into how cells stick to each other and to other bodily structures, an essential function in the formation of tissue structures and organs. It’s thought that abnormalities in their ability to do so play an important role in a broad range of disorders.

Fish grazing on coral reefs

Video Study Shows Picky Eater Fish Threaten Endangered Coral Reefs

February 12, 2013 — Using underwater video cameras to record fish feeding on South Pacific coral reefs, scientists have found that herbivorous fish can be picky eaters – a trait that could spell trouble for endangered reef systems.

Agilent Lab at Georgia Tech

Agilent Technologies Commits $90 Million Gift of Software to Georgia Institute of Technology

February 4, 2013 — Agilent Technologies Inc. (NYSE: A) today announced the largest in-kind software donation ever in its longstanding relationship with the Georgia Institute of Technology.

Troposphere-Microbiome-Sampling

Study Finds Substantial Microorganism Populations in the Upper Troposphere

January 28, 2013 — In what is believed to be the first study of its kind, researchers used genomic techniques to document the presence of significant numbers of living microorganisms – principally bacteria – in the middle and upper troposphere, that section of the atmosphere approximately four to six miles above the Earth’s surface.

Bursting a Bacteria Cell Wall

Study Quantifies the Size of Holes Antibacterials Create in Cell Walls to Kill Bacteria

January 9, 2013 — Researchers recently created a biophysical model of the response of a Gram-positive bacterium to the formation of a hole in its cell wall, then used experimental measurements to validate the theory, which predicted that a hole in the bacteria cell wall larger than 15 to 24 nanometers in diameter would cause the cell to lyse, or burst.

Female Rotifer

Gulf of Mexico Clean-Up Makes 2010 Spill 52-Times More Toxic

November 30, 2012 — If the 4.9 million barrels of oil that spilled into the Gulf of Mexico during the 2010 Deep Water Horizon spill was a ecological disaster, the two million gallons of dispersant used to clean it up apparently made it even worse – 52-times more toxic. That’s according to new research from the Georgia Institute of Technology and Universidad Autonoma de Aguascalientes (UAA), Mexico.

Online scheduler vaccination

Online Tool Creates Catch-Up Immunization Schedules for Missed Childhood Vaccinations

November 28, 2012 — A new online tool takes the guesswork out of developing individualized catch-up immunization schedules by allowing parents and health care providers to easily create a schedule that ensures missed vaccines and future vaccines are administered according to approved guidelines.

Measles vaccination

Microneedle Patch May Advance World Measles Vaccination Effort

November 27, 2012 — Measles vaccine given with painless and easy-to-administer microneedle patches can immunize against measles at least as well as vaccine given with conventional hypodermic needles, according to research done by the Georgia Institute of Technology and the Centers for Disease Control and Prevention (CDC).

Microbial diversity

Research Will Study How Diversity Helps Microbial Communities Respond to Change

November 26, 2012 — Researchers at the Georgia Institute of Technology have received a five-year, $1.8 million grant from the National Science Foundation (NSF) to study how complex microbial systems use their genetic diversity to respond to human-induced change. The work is important because these microbial communities play critical roles in the environment, breaking down pollutants, recycling nutrients – and serving as major sources of nitrogen and carbon.

Greg Gibson

NIH awards Georgia malaria research consortium up to $19.4 million contract

November 19, 2012 — The research team will use the comprehensive research approach of systems biology to study and catalog in molecular detail how malaria parasites interact with their human and animal hosts.

Whale Shark 1

New Whale Shark Study Used Metabolomics to Help Understand Shark and Ray Health

November 19, 2012 — New research from Georgia Aquarium and Georgia Institute of Technology provides evidence that a suite of techniques called “metabolomics” can be used to determine the health status of whale sharks (Rhincodon typus), the world’s largest fish species. The study, led by Dr. Alistair Dove, director of Research & Conservation at Georgia Aquarium and an adjunct professor at Georgia Tech, found that the major difference between healthy and unhealthy sharks was the concentration of homarine in their in serum—indicating that homarine is a useful biomarker of health status for the species.

Athanassios Sambanis

Georgia Tech Awarded $1.2 Million Diabetes Training Grant

November 8, 2012 — The Innovation and Leadership in Engineering Technologies and Therapies for diabetes postdoctoral training grant is a cross-disciplinary training program in cell- and tissue-based therapies and novel insulin delivery technologies.

Mutualistic fish

Corals Attacked by Toxic Seaweed Use Chemical 911 to Summon Help

November 8, 2012 — Corals under attack by toxic seaweed do what anyone might do when threatened – they call for help. A study reported this week in the journal Science shows that threatened corals send signals to fish “bodyguards” that quickly respond to trim back the noxious alga.

Cathepsin prediction

Blood Testing Predicts Level of Enzymes that Facilitate Disease Progression

November 1, 2012 — Researchers are developing a technique for predicting from a simple blood sample the amount of cathepsins—protein-degrading enzymes known to accelerate certain diseases—a specific person would produce. This patient-specific information may be helpful in developing personalized approaches to treat these tissue-destructive diseases.

Grid cell firing pattern

Primates’ Brains Make Visual Maps Using Triangular Grids, Study Shows

October 28, 2012 — Primates’ brains see the world through triangular grids, according to a new study published online October 28 in the journal Nature.

Gilda Barabino

Georgia Tech and Emory University Host Annual Biomedical Engineering Meeting

October 22, 2012 — Nearly 4,000 biomedical engineers from around the world will gather in Atlanta Oct. 24-27 for the annual conference, hosted by the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. 

Craig Forest robotic neural recordings

Georgia Tech, MIT and Allen Institute for Brain Science Receive $4.3 Million NIH Grant

October 9, 2012 — An interdisciplinary team from the Georgia Tech, MIT and the Allen Institute for Brain Science was awarded a $4.3 million National Institutes of Health grant. 

Squeezing Cancer Cells 1

Squeezing Ovarian Cancer Cells to Predict Metastatic Potential

October 5, 2012 — New Georgia Tech research shows that cell stiffness could be a valuable clue for doctors as they search for and treat cancerous cells before they’re able to spread. The findings, which are published in the journal PLoS One, found that highly metastatic ovarian cancer cells are several times softer than less metastatic ovarian cancer cells.

Polymer Nerve Guide

Study Suggests Immune System Can Boost Regeneration of Peripheral Nerves

October 2, 2012 — Modulating immune response to injury could accelerate the regeneration of severed peripheral nerves, a new study in an animal model has found. By altering activity of the macrophage cells that respond to injuries, researchers dramatically increased the rate at which nerve processes regrew.

High-Interference Object Perception

Eliminating Visual Clutter Helps People with Mild Cognitive Impairment

October 1, 2012 — A new study from Georgia Tech and the University of Toronto suggests that memory impairments for people diagnosed with early stage Alzheimer’s disease may be due, in part, to problems in determining the differences between similar objects. The findings also support growing research indicating that a part of the brain once believed to support memory exclusively – the medial temporal lobe - also plays a role in object perception.

Remotoscope

iPhone Attachment Designed for At-Home Diagnoses of Ear Infections

September 18, 2012 — Soon, parents may be able to skip the doctor’s visit and receive a diagnosis without leaving home by using Remotoscope, a clip-on attachment and software app that turns an iPhone into an otoscope. 

Studying Trinucleotide Repeats

Study Identifies Genes Associated with Genomic Expansions that Cause Disease

September 9, 2012 — A study of more than 6,000 genes in a common species of yeast has identified the pathways that govern the instability of GAA/TTC repeats. In humans, the expansions of these repeats is known to inactivate a gene – FXN – which leads to Friedreich’s ataxia, a neurodegenerative disease that is currently incurable. In yeast, long repeats also destabilize the genome, manifested by the breakage of chromosomes. 

Chimpanzee

More Clues About Why Chimps and Humans Are Genetically Different

August 23, 2012 — In research published in September’s American Journal of Human Genetics, Soojin Yi looked at brain samples of each species. She found that differences in certain DNA modifications, called methylation, may contribute to phenotypic changes. The results also hint that DNA methylation plays an important role for some disease-related phenotypes in humans, including cancer and autism.

Ross Ethier

C. Ross Ethier Joins Coulter Department of Biomedical Engineering at Georgia Tech and Emory University

August 22, 2012 — C. Ross Ethier, Ph.D., an internationally recognized leader in the area of biomechanics and mechanobiology recently joined the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University as the new Georgia Research Alliance Lawrence L. Gellerstedt, Jr. Eminent Scholar in Bioengineering. He is considered one of the world’s leading researchers in the study of glaucoma, arterial disease and osteoarthritis. 

Automated Worm Sorter2

Automated Worm Sorter Detects Subtle Differences in Tiny Animals Used in Genetic Research

August 19, 2012 — Scientists have demonstrated an automated system that uses artificial intelligence and cutting-edge image processing to rapidly examine large numbers of individual nematodes, a tiny animal widely used in biological research.

Manu Platt, PhD - Assistant Professor, Department of Biomedical Engineering

Cathepsin Cannibalism: Enzymes Attack One Another Instead of Harming Proteins

August 13, 2012 — Researchers for the first time have shown that members of a family of enzymes known as cathepsins – which are implicated in many disease processes – may attack one another instead of the proteins they normally degrade. Dubbed “cathepsin cannibalism,” the phenomenon may help explain problems with drugs that have been developed to inhibit the effects of these powerful proteases.

John McDonald

Using Millions of Years of Cell Evolution in the Fight Against Cancer

August 7, 2012 — Professor John McDonald is studying micro RNAs (miRNAs), a class of small RNAs that interact with messenger RNAs (mRNAs) that have been linked to a number of diseases, including cancer. McDonald’s lab placed two different miRNAs (MiR-7 and MiR-128) into ovarian cancer cells and watched how they affected the gene system.

Microneedles for Ocular Injection3

Researchers Show Potential of Microneedles to Target Drugs to the Back of the Eye

July 23, 2012 — Thanks to tiny microneedles, eye doctors may soon have a better way to treat diseases such as macular degeneration that affect tissues in the back of the eye. That could be important as the population ages and develops more eye-related illnesses – and as pharmaceutical companies develop new drugs that otherwise could only be administered by injecting into the eye with a hypodermic needle.

Single Molecule Identification

Compressed Sensing Allows Super-Resolution Microscopy Imaging of Live Cell Structures

April 22, 2012 — Researchers have advanced scientists’ ability to view a clear picture of a single cellular structure in motion. By identifying molecules using compressed sensing, this new method provides needed spatial resolution plus a faster temporal resolution than previously possible.

Preparing FT-IR Equipment

Scientists Study the Catalytic Reactions Used by Plants to Split Oxygen from Water

April 2, 2012 — Green plants produce oxygen from water using a catalytic technique powered by sunlight. Scientists have now shown the importance of a hydrogen-bonding water network to that process -- which is the major source of the Earth's oxygen.

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